AMU Medical AMU Solved Paper-1995

  • question_answer
    A class of mutation induced by addition or deletion of a nucleotide is called

    A)  missense         

    B)  nonsense

    C)  substitution       

    D)  frameshift.

    Correct Answer: D

    Solution :

    : Frame shift mutations result from deletion or insertion of nucleotides in DNA that generates altered mRNAs. The deletion or addition of a single nucleotide in a coding strand of a gene results in an altered reading frame in the mRNA. The machinery translating the mRNA does not recognize that a base is added or missing, because there is no punctuation in the reading of codons. Thus a major alteration in the sequence of polymerized amino acids results.


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