A) increases the affinity of haemoglobin to both oxygen and hydrogen
B) increases the affinity of haemoglobin to oxygen but decreases its affinity to hydrogen
C) decreases the affinity of haemoglobin to oxygen but increases its affinity to hydrogen
D) decreases the affinity of haemoglobin to both oxygen and hydrogen
Correct Answer: C
Solution :
In tissue high concentration of \[C{{O}_{2}}\] results in dissociation of oxyhaemoglobin. One molecule of haemoglobin combines with 4 molecules of oxygen to form oxyhaemoglobin (the form, in which most oxygen is carried from the lungs to the tissues). \[\underset{\left( Haemoglobin \right)}{\mathop{Hb}}\,+\underset{\left( oxygen \right)~}{\mathop{{{O}_{2}}}}\,\xrightarrow{{}}\underset{\left( oxyhaemoglobin \right)}{\mathop{Hb{{O}_{2}}}}\,\] As pH decreases or \[{{P}_{C{{O}_{2}}}}\] increases, the affinity for oxygen decreases so less. Oxygen, which combines with haemoglobin is available to tissue. \[Hb{{O}_{2}}+C{{O}_{2}}\xrightarrow{{}}HbC{{O}_{2}}+{{O}_{2}}\]
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