A) thalassaemia
B) sickle cell anaemia
C) haemophilia
D) leukaemia
Correct Answer: B
Solution :
Pleiotropic gene has more than one effect in an organism, eg, sickle cell anaemia which results due to abnormal haemoglobins. Thalassaemia is a blood disease caused by a substitution mutation in the DNA sequence that controls the synthesis of the \[\alpha \] or\[\beta \]-chain of haemoglobin. It results in anaemia and growth retardation. Haemophilia is a hereditary sex-linked disease, in which there is a deficiency or defect of factor-VIII, causing the blood to clot very slowly. Leukaemia or Cancer of WBCs is any disorder of cell growth that results in invasion destruction of surrounding healthy tissue by normal cells.
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