AMU Medical AMU Solved Paper-2005

  • question_answer
    The globular proteins undergo structural changes, in response to extremes of pH or temperature, is called

    A)  renaturation                    

    B)  denaturation

    C)  combination                     

    D)  Both (a) and (b)

    Correct Answer: B

    Solution :

                     Functional three dimensional form of a protein is called native state. The state is maintained by specific bonds that forms its quaternary, tertiary and secondary structure. These bonds are easily broken by high temperature, change in pH, detergent, high energy radiation. This process of degrading tertiary structure of protein is known as denaturation. Renaturation is the process, in which these occurs reestablishment of the bonds due to removal of denaturation agent for maintenance of tertiary structure.


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