AMU Medical AMU Solved Paper-2010

  • question_answer
    In citric acid cycle, decarboxylarion occurs when

    A)  citric acid converts to                                                                                                                   \[\alpha\] -ketoglutaric acid

    B)  succinic acid converts to malic acid

    C)  malic acid converts to oxaloacetic acid

    D)  oxaloacetic acid converts to citric acid

    Correct Answer: A

    Solution :

                     In citric acid cycle, decarboxylation is the first step, where a carbon group is lost as carbon dioxide in a decarboxylation reaction. The remaining compound now has 5 carbons and is called alpha-ketoglutaric acid. This reaction is also catalysed by isocitrate dehydrogenase.


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