AMU Medical AMU Solved Paper-2010

  • question_answer
    In  the  clotting  mechanism  pathway, thrombin activates factors

    A)  XI, VIII, V                           

    B)  XI, IX, X

    C)  VIII, X, V                                             

    D)  IX, VIII, X

    Correct Answer: A

    Solution :

                     When blood vessels are cut or damaged, the loss of blood from the system must be stopped before shock and possible death occur. This is accomplished by solidification of the blood, a process called coagulation or clotting. A blood clot consists of a plug of platelets enmeshed in a network of insoluble fibrin molecules. Platelet aggregation and fibrin formation both require the proteolytic enzyme thrombin. As thrombin is generated, it activates more Factor-V, Factor-VIII, and Factor-XL


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