AMU Medical AMU Solved Paper-2010

  • question_answer
    In humans, the oocyte is maintained in a state of meiotic arrest by secretions of

    A)  granulosa cells                 

    B)  zona pellucida

    C)  cumulus oophorus        

    D)  theca

    Correct Answer: A

    Solution :

                     A granulosa cell or follicular cell is a somatic cell of the sex cord that is closely associated with the developing female gamete (called an oocyte or egg) in the ovary of mammals. In the primary ovarian follicle and later in foflicle development (folliculogenesis), granulosa cells advance to form a multilayered cumulus oophorus surrounding the oocyte in the preovulatory or Graafian follicle. The major functions of granulosa cells include the production of sex steroids, as well as myriad of growth factors thought to interact with the oocyte during its development.


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