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AMU Medical AMU Solved Paper-2010

  • question_answer
    Immediate hypersensitivity which result in the  release  of histamine  and  other inflammatory substances is mediated by

    A)  IgA                                       

    B)  IgD

    C)  IgE                                        

    D)  IgG

    Correct Answer: C

    Solution :

                     Immunoglobulin E (IgE) normally has very low concentrations in blood and connective tissues, but it plays a crucial role in allergic reactions. It binds to mast cells and when triggered by the presence of antigen, causes histamine release and hence inflammation and other common allergic symptoms.


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