AMU Medical AMU Solved Paper-2015

  • question_answer
    Which of the following is most appropriate regarding kidney function regulation? Stimulation of

    A)  Renin-angiotensin mechanism decreases the Glomerular Filtration Rate (GFR) while atrial natriuretic factor increase GFR

    B)  Renin-angiotensin mechanism increase GFR while atrial natriuretic factor decreases GFR

    C)  Renin-angiotensin   mechanism   and   atrial natriuretic factor both increase the GFR

    D)  Renin-angiotensin   mechanism   and   atrial natriuretic factor both decrease the GFR

    Correct Answer: B

    Solution :

                    Renin Angiotensin mechanism increases the Glomerular Filtration Rate (GFR), while atrial natriuretic factor decreases GFR. A reduced blood pressure causes reduced GFR, result in release of renin by juxta glomerular cells. Renin    converts angiotensinogen into angiotensin-II and angiotensin-II. The latter increases the BP by constriction of arterioles and thus increase GFR. ANF is produced by atria of heart and results in decrease blood pressure by reducing\[{{H}_{2}}O\], Na and adipose loads on circulatory system.


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