BHU PMT BHU PMT (Mains) Solved Paper-2007

  • question_answer

    Directions : In the following question more than one of the answers given may be correct. Select the correct answer and mark it according to the code:

    Which of the following factors raise the \[{{\text{P}}_{\text{50}}}\] value and shifts the \[Hb{{O}_{2}}\]dissociation curve to right and vice versa ? (1) Rise in \[PC{{O}_{2}}\] (2) Rise in H+ ions (= fall in pH) (3) Fall in temperature (4) Fall in diphosphoglyceric acid

    A)  1, 2 and 3 are correct    

    B)  1 and 2 are correct

    C)  2 and 4 are correct         

    D)  1 and 3 are correct

    Correct Answer: B

    Solution :

                     A rise in body temperature, concentration of 2,3 diphosphoglycerate (DPG) in RBCs or \[{{P}_{C{{O}_{2,}}}}\]or a fall in blood pH (increase H+), decreases \[{{\text{O}}_{\text{2}}}\text{-}\]affinity of haemoglobin revising \[{{P}_{50}}\]and shirting the \[{{\text{O}}_{\text{2}}}\text{-}\]haemoglobin dissociation curve to the right,


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