A) change of amino acid in \[\text{ }\!\!\alpha\!\!\text{ -}\]chain of haemoglobin
B) change of amino add in \[\text{ }\!\!\beta\!\!\text{ -}\]chain of haemoglobin
C) change of amino acid in both \[\text{ }\!\!\alpha\!\!\text{ -}\] and \[\text{ }\!\!\beta\!\!\text{ -}\] chains of haemoglobin
D) change of amino acid in either \[\text{ }\!\!\alpha\!\!\text{ -}\] or \[\text{ }\!\!\beta\!\!\text{ -}\] chain of haemoglobin
Correct Answer: B
Solution :
The sixth amino acid from the amino terminal end of \[\text{ }\!\!\beta\!\!\text{ -}\]chain of normal haemoglobin is glutamic acid while in sickle cell haemoglobin, it is valine. It results a change in confirmation of the haemoglobin molecule and the RBC becomes sickle shaped.
You need to login to perform this action.
You will be redirected in
3 sec
