A) the pro Bt toxin activation requires temperature above human body temperature
B) the Bt toxin recognises only insect specific target
C) the Bt toxin formation from pro Bt toxin requires pH lower than that present in human stomach
D) conversion of pro Bt toxin to Bt toxin takes place only in highly alkaline conditions
E) None of the above
Correct Answer: D
Solution :
The \[Bt\] toxin protein exist as inactive proctoreins, but once an insects ingest the inactive toxin, it is converted into an active form of toxin due to the alkaline pH of the gut which solubilise the crystals. The activated toxin binds to the surface of midgut epithelial cells and create pores that causes cell swelling and lysis and eventically cause death of the insect.You need to login to perform this action.
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