DUMET Medical DUMET Medical Solved Paper-2001

  • question_answer
    When acetamide reacts with \[B{{r}_{2}}\] in presence of \[NaOH\], there is a formation of:

    A)  \[C{{H}_{3}}N{{H}_{2}}\]

    B)  \[C{{H}_{3}}CN\]

    C)  \[C{{H}_{3}}C{{H}_{2}}OH\]  

    D)  \[C{{H}_{3}}CHO\]

    Correct Answer: A

    Solution :

    \[C{{H}_{3}}CON{{H}_{2}}+B{{r}_{2}}+4NaOH\xrightarrow{\Delta }\underset{methyla\min e}{\mathop{C{{H}_{3}}N{{H}_{2}}}}\,\] \[+N{{a}_{2}}C{{O}_{3}}+2NaBr+2{{H}_{2}}O\] This is Hofmann bromamide reaction in which amide reacts with KOH and bromine to form amine having one carbon atom less than parent amide.


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