DUMET Medical DUMET Medical Solved Paper-2009

  • question_answer
    Downs syndrome is due to

    A)  linkage

    B)  sex-linked inheritance

    C)  crossing over

    D)  non-disjunction of chromosome

    Correct Answer: D

    Solution :

    Downs syndrome or Mongolian idiocy is due to trisomy of 21 chromosome. It is caused by son-disjunction of 21st chromosome pair during anaphase-I. This syndrome is characterised by rounded face with broad fore-head, open mouth with protruding tongue and projecting lower lip, small flat hands with stubby little finger, mentally retarded and underdeveloped gonads and genitals.


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