J & K CET Medical J & K - CET Medical Solved Paper-2001

  • question_answer
    Which reagent can be used for the alkylation of aromatic nitro compounds?

    A)  Methyl-sulfinyl carbanion

    B)  Methyl-iodide

    C)  Dimethyl-sulphate

    D)  Methyl-lithium

    Correct Answer: A

    Solution :

                    The\[N{{O}_{2}}\]group is ring deactivating group. Hence, it does not favour electrophilic alkylation in benzene. Nitrobenzene undergoes nucleophilic   alkylation   by   carbanion intermediate.   Hence,   methyl   sulphinyl carbanion is used for the alkylation of aromatic nitro compounds.


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