J & K CET Medical J & K - CET Medical Solved Paper-2003

  • question_answer
    The compound obtained by heating a mixture of\[{{1}^{o}}\]amine and chloroform with ethanolic potassium hydroxide is:

    A)  an alkyl isocyanide

    B)  an alkyl isothiocyanate

    C)  an amide

    D)  an amide and nitro compound

    Correct Answer: A

    Solution :

                    Primary amines on heating with chloroform and ethanolic\[KOH,\]give alkyl isocyanide. This reaction is called carbylamine reaction. \[\underset{{{1}^{o}}\text{ }amine}{\mathop{R-N{{H}_{2}}}}\,+CHC{{l}_{3}}+\underset{(alcohol)}{\mathop{3KOH}}\,\xrightarrow[{}]{\Delta }\underset{alkyl\text{ }isocyanide}{\mathop{R-NC}}\,\]                                                 \[+3KCl+3{{H}_{2}}O\]


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