J & K CET Medical J & K - CET Medical Solved Paper-2012

  • question_answer
    The protein whose removal enables myosin to bind actin in smooth muscle is

    A)  tropomyosin

    B)  caldesmon

    C)  myosin light chain kinase

    D)  calmodulin

    Correct Answer: D

    Solution :

     In place of troponin smooth muscle cells contain a large amount of another regulatory protein called calmodulin. It initiate contraction by activating the myosin cross- bridge. The steps in contraction are (i) The\[C{{a}^{2+}}\]ions bind with calmodulin (ii) The calmodulin calcium combination join with and activate mysoin-kinase, a phosphorylating enzyme. (iii) One of the light chains of each myosin head becomes phosphorylated by this enzyme and the head has capability of binding repeatedly with actin filament.


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