J & K CET Medical J & K - CET Medical Solved Paper-2013

  • question_answer
    The product of an enzyme-catalysed reaction can act as an inhibitor of the reaction. This mechanism of control is known as

    A)  feed back inhibition

    B)  competitive inhibition

    C)  represssion

    D)  non-competitive inhibition

    Correct Answer: B

    Solution :

     According to lock and key hypothesis, proposed by Emil Fisher, the active site of enzyme possess special group with weak bonds and a configuration complementary to the shape of substrate molecule. Enzyme substrate complex (ES complex) is formed by the joining of two. This hypothesis is also called as enzyme substrate complex theory. The hypothesis is able to explain competitive inhibition in which a substances having a similar structure to substrate blocks the active site of the enzyme just as wrong but related key gets jammed in a lock (substrate).


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