JIPMER Jipmer Medical Solved Paper-2007

  • question_answer
    . During which stage in the complete oxidation of glucose is the greatest number of ATP molecules formed from ADP?

    A)  Conversion of pyruvic acid to acetyl Co-A

    B)  Electron transport chain

    C)  Glycolysis

    D)  Krebs cycle

    Correct Answer: B

    Solution :

    In glycolysis 4 ATP and \[2\,NAD{{H}_{2}}\] molecules are formed. These \[2\,NAD{{H}_{2}}\] molecules go to electron transport chain. In oxidative decarboxylation no ATP molecule is formed but two molecules of \[NAD{{H}_{2}}\] are formed from two molecules of pyruvate. These two \[NAD{{H}_{2}}\] go to electron transport chain. In Krebs cycle 2 ATP, 6 NADH, and \[2\,FAD{{H}_{2}}\] molecules are formed from two molecule of acetyl Co- A. These \[NAD{{H}_{2}}\] and \[2\,FAD{{H}_{2}}\], go to electron transport chain. In electron transport chain all \[NAD{{H}_{2}}\] and \[FAD{{H}_{2}}\] pass to electron carriers and yield 3 ATP and 2 ATP molecules per \[NAD{{H}_{2}}\] and \[FAD{{H}_{2}}\] respectively. Thus, 4 ATP are formed in glycolysis 2 ATP in Krebs cycle and \[\frac{\text{34 ATP from electron transport chain}}{\text{4}0\text{ ATP}}\] 2 ATP molecules are used during glycolysis. So, net gain of ATP molecules during one complete oxidation of a glucose molecule is 38 ATP.


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