Manipal Medical Manipal Medical Solved Paper-2014

  • question_answer
    The increasing order of relative ease of protonation of the indicated nitrogen is

    A) \[1<2<3<4\]                          

    B) \[4<3<2<1\]

    C) \[3<2<4<1\]                          

    D) \[1<4<2<3\]

    Correct Answer: D

    Solution :

    N-1 is least basic followed by N-4 as they are amide nitrogen?s and lone pair of N-1 is more delocalised with two adjacent carbonyls. N-3 is most basic as lone pair of N-2 is part of aromaticity.


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