WB JEE Medical WB JEE Medical Solved Paper-2015

  • question_answer
    Which one of the following components of urine in a healthy human does not differ much in concentration from that of blood plasma?

    A) \[N{{H}_{4}}^{+}\]

    B)  \[{{K}^{+}}\]

    C)  \[N{{a}^{+}}\]

    D)  \[S{{O}_{4}}^{2-}\]

    Correct Answer: D

    Solution :

     Renal threshold is the concentration of a substance dissolved in the blood-plasma above which of the kidneys begin to remove it into the urine. When the renal threshold is exceeded, reabsorption of the substance by the PCT is incomplete. Consequently, part of the substance remains in the urine. \[S{{O}_{4}}^{2-},\]creatinine and other metabolic end products are the non-threshold substances which are not at all reabsorbed and are excreted in urine even under normal conditions. Thats why these substances do not differ much in concentration from that of blood plasma. \[N{{a}^{+}},{{K}^{+}},\]glucose, \[C{{a}^{2+}}\]are thehigh-threshold substances,  which  are  reabsorbed  very extensively and do not appear in urine under normal conditions. These appear in urine only if their concentration in plasma is abnormally high or in renal diseases when reabsorption is affected. \[N{{H}_{4}}^{+}\]is excreted in the form of urea. Urea, uric acid and phosphate are the low-threshold substances which are reabsorbed to a little extent and appear in urine even under normal conditions.


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