have active sites which bind the substrate for carrying out chemical reactions
quickly and effectively.
The functional groups present at the active site of enzyme interact with
functional groups of substrate" through ionic bonding, hydrogen bonding,
van der Waals interactions, etc. Some drugs interfere with this interaction by
blocking the binding site of enzyme thereby preventing the binding of actual substrate
with the enzyme. As a result, catalytic activity of enzyme is inhibited and the
drugs which inhibit the catalytic activity of enzymes are called inhibitors.
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