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KVPY Sample Paper KVPY Stream-SX Model Paper-15

  • question_answer
    Ahexapeptide has the composition Ala, Gly, Phe, Val. Both the N-terminal and C-terminal units are Val. Cleavage of the hexapeptide by chemotrypsin gives two different tripeptides, both having Val as the N-terminal group. Among the products of randod hydrolysis is a Ala-Val dipeptide fragment. What is the primary structure of the hexapeptide?

    A) Val-Galy-Phe-Val-Al-a-Val

    B) Val-Ala-Phe-Val-Gly-Val

    C) Val-Gly-Ala-Val-Phe-Val

    D) Val-Phe-Val-Ala-Gly-Val

    Correct Answer: A

    Solution :

    \[Val\text{-}\,Gly\text{-}Phe\text{-}Val\text{-}Ala\text{-}Val\] Random hydrolysis gives Ala-Val dipeptide fragment, which indicates the connected presence of Ala and Val. Thus, the correct sequence is given in option [a].


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