AMU Medical AMU Solved Paper-2012

  • question_answer
    Which one of the following compounds cannot be used for the preparation of Grignard reagent?

    A)  \[{{C}_{2}}{{H}_{5}}Br\]

    B)  \[HO-C{{H}_{2}}C{{H}_{2}}Cl\]

    C)  \[{{C}_{6}}{{H}_{5}}C{{H}_{2}}Cl\]

    D)  \[C{{H}_{2}}=CH-C{{H}_{2}}Cl\]

    Correct Answer: B

    Solution :

                     Grignard reagent readily reacts with compounds containing active hydrogen such as alcohols. Unsaturated halides on reaction with Grignard reagent give alkens. \[\underset{Grignard\text{ }reagent}{\mathop{C{{H}_{3}}MgCl}}\,\,\,+ClC{{H}_{2}}-CH=C{{H}_{2}}\xrightarrow{{}}\]                                 \[\underset{but-1-ene}{\mathop{C{{H}_{3}}C{{H}_{2}}CH}}\,=C{{H}_{2}}+MgB{{r}_{2}}\]


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